Integrating Bulk and Single-Cell Transcriptomic Data to Identify Ferroptosis-Associated Inflammatory Gene in Alzheimer’s Disease
This study reveals the key role of SLC11A1 in AD, particularly in the context of ferroptosis and immune inflammation. It provides a novel molecular mechanistic perspective and offers potential targets for future therapeutic strategies.
Authors
- Gaihua Zhang (ORCID: https://orcid.org/0000-0003-1038-1049)
- Bingqing Li
- Huasheng Liu (ORCID: https://orcid.org/0000-0002-2635-999X)
- Yuting Peng (ORCID: https://orcid.org/0000-0003-2349-2231)
- Jian Wang (ORCID: https://orcid.org/0000-0002-9482-5227)
- Xinhua Huo
- Huiqin Zhou (ORCID: https://orcid.org/0000-0002-3041-4365)
Institutions
- Central South University (CN)
- Hunan Normal University (CN)
- National Engineering Research Center of Human Stem Cells (CN)
- Third Xiangya Hospital (CN)
Publication Details
- Journal
- Journal of Inflammation Research
- Published
- 2025-02-01
- DOI
- https://doi.org/10.2147/jir.s497418
- Citations
- 8
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 7.49