Assessment the real-world safety of intravitreal dexamethasone implant (Ozurdex): novel insights from a comprehensive pharmacovigilance analysis utilizing the FAERS database
While Dex remains an effective treatment option for ocular conditions, its use is associated with significant risks, particularly regarding unexpected and severe complications such as corneal decompensation. Continuous pharmacovigilance and detailed patient monitoring are essential to mitigate these risks. Future studies should focus on prospective designs and comprehensive clinical data to better understand the safety profile of Dex.
Authors
- Chao-fu Zhao
- Lina Lan (ORCID: https://orcid.org/0000-0002-2970-5712)
- Xing-yu Shi
- Shipei Fan
- Jun Li (ORCID: https://orcid.org/0000-0002-8942-2896)
Institutions
- Wenzhou Medical University (CN)
- Lishui Central Hospital (CN)
Publication Details
- Journal
- BMC Pharmacology and Toxicology
- Published
- 2025-02-10
- DOI
- https://doi.org/10.1186/s40360-025-00866-7
- Citations
- 4
- Primary Topic
- Retinal and Optic Conditions
- Type
- article
- Field-Weighted Citation Impact
- 6.83