Assessment the real-world safety of intravitreal dexamethasone implant (Ozurdex): novel insights from a comprehensive pharmacovigilance analysis utilizing the FAERS database

While Dex remains an effective treatment option for ocular conditions, its use is associated with significant risks, particularly regarding unexpected and severe complications such as corneal decompensation. Continuous pharmacovigilance and detailed patient monitoring are essential to mitigate these risks. Future studies should focus on prospective designs and comprehensive clinical data to better understand the safety profile of Dex.

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Publication Details

Journal
BMC Pharmacology and Toxicology
Published
2025-02-10
DOI
https://doi.org/10.1186/s40360-025-00866-7
Citations
4
Primary Topic
Retinal and Optic Conditions
Type
article
Field-Weighted Citation Impact
6.83
Controls
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article

Assessment the real-world safety of intravitreal dexamethasone implant (Ozurdex): novel insights from a comprehensive pharmacovigilance analysis utilizing the FAERS database

Chao-fu Zhao, Lina Lan, Xing-yu Shi, Shipei Fan et al.
4 citations
BMC Pharmacology and Toxicology
Retinal and Optic Conditions
6.83
article

Assessment the real-world safety of intravitreal dexamethasone implant (Ozurdex): novel insights from a comprehensive pharmacovigilance analysis utilizing the FAERS database

Chao-fu Zhao, Lina Lan, Xing-yu Shi, Shipei Fan, Jun Li
article en
4 citations

Abstract

While Dex remains an effective treatment option for ocular conditions, its use is associated with significant risks, particularly regarding unexpected and severe complications such as corneal decompensation. Continuous pharmacovigilance and detailed patient monitoring are essential to mitigate these risks. Future studies should focus on prospective designs and comprehensive clinical data to better understand the safety profile of Dex.

BMC Pharmacology and ToxicologyVol. 26(1)
Wenzhou Medical University (CN), Lishui Central Hospital (CN)
Zero hunger
Openalex Percentile: Top 4%
Retinal and Optic Conditions
6.83
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