COMPARATIVE CROSS SECTIONAL STUDY OF EFFECT OF 0.5% HEAVY BUPIVACAINE VERSUS 0.5% HEAVY BUPIVACAINE + FENTANYL 25 MCG ON NEWBORN APGAR SCORE BORN TO TERM GESTATION MOTHER BY LOWER SEGMENT CESAREAN SECTION (LSCS) UNDER SUBARACHNOID BLOCK

Objectives: The scientific aim of anesthesiology is to temporarily eliminate pain. This goal was first established for surgical pain management, but it has since expanded to include post-operative pain management, chronic pain management, and cancer pain management. Methods: Sixty patients from ASA I and II who were scheduled for elective cesarean sections participated in a comparative cross-sectional study. The patients were divided into two groups at random, Group F and Group B. Fentanyl 25 mcg and 0.5% hyperbaric buprevacaine 12.5 mg were administered intrathecally to parturients in Group F. Group B parturients got 12.5 mg of 0.5% hyperbaric buprevacaine intravenously. Results: The two groups’ appearance, pulse, grimace, activity, and respiration (APGAR) scores were compared, and the neonatal APGAR score was unaffected by the intrathecal administration of fentanyl to buprevacaine. In both groups, the durations of sensory blockade onset, motor blockade onset, and resolution to bromage 0 were statistically insignificant. When compared to Group B, group F displayed longer durations for both two-segment regression and total sensory blocking. When compared to Group B, Group F had a lower frequency of side effects such as nausea, vomiting, and shivering. Conclusions: We come to the conclusion that, in elective cesarean sections, 0.5% heavy Bupivacaine combined with 25 mcg of fentanyl is preferable to 0.5% heavy Bupivacaine alone.

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Journal
Asian Journal of Pharmaceutical and Clinical Research
Published
2025-02-07
DOI
https://doi.org/10.22159/ajpcr.2025v18i2.53595
Primary Topic
Anesthesia and Pain Management
Type
article
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article

COMPARATIVE CROSS SECTIONAL STUDY OF EFFECT OF 0.5% HEAVY BUPIVACAINE VERSUS 0.5% HEAVY BUPIVACAINE + FENTANYL 25 MCG ON NEWBORN APGAR SCORE BORN TO TERM GESTATION MOTHER BY LOWER SEGMENT CESAREAN SECTION (LSCS) UNDER SUBARACHNOID BLOCK

Akshay Muralidhar, A. Ali, REGALLA KINNERA, B VENKATESWARARAO
Asian Journal of Pharmaceutical and Clinical Research
Anesthesia and Pain Management
article

COMPARATIVE CROSS SECTIONAL STUDY OF EFFECT OF 0.5% HEAVY BUPIVACAINE VERSUS 0.5% HEAVY BUPIVACAINE + FENTANYL 25 MCG ON NEWBORN APGAR SCORE BORN TO TERM GESTATION MOTHER BY LOWER SEGMENT CESAREAN SECTION (LSCS) UNDER SUBARACHNOID BLOCK

Akshay Muralidhar, A. Ali, REGALLA KINNERA, B VENKATESWARARAO
article en

Abstract

Objectives: The scientific aim of anesthesiology is to temporarily eliminate pain. This goal was first established for surgical pain management, but it has since expanded to include post-operative pain management, chronic pain management, and cancer pain management. Methods: Sixty patients from ASA I and II who were scheduled for elective cesarean sections participated in a comparative cross-sectional study. The patients were divided into two groups at random, Group F and Group B. Fentanyl 25 mcg and 0.5% hyperbaric buprevacaine 12.5 mg were administered intrathecally to parturients in Group F. Group B parturients got 12.5 mg of 0.5% hyperbaric buprevacaine intravenously. Results: The two groups’ appearance, pulse, grimace, activity, and respiration (APGAR) scores were compared, and the neonatal APGAR score was unaffected by the intrathecal administration of fentanyl to buprevacaine. In both groups, the durations of sensory blockade onset, motor blockade onset, and resolution to bromage 0 were statistically insignificant. When compared to Group B, group F displayed longer durations for both two-segment regression and total sensory blocking. When compared to Group B, Group F had a lower frequency of side effects such as nausea, vomiting, and shivering. Conclusions: We come to the conclusion that, in elective cesarean sections, 0.5% heavy Bupivacaine combined with 25 mcg of fentanyl is preferable to 0.5% heavy Bupivacaine alone.

Asian Journal of Pharmaceutical and Clinical Research
Osmania Medical College (IN)
Good health and well-being
Openalex Percentile: Top 96%
Anesthesia and Pain Management
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COMPARATIVE CROSS SECTIONAL STUDY OF EFFECT OF 0.5% HEAVY BUPIVACAINE VERSUS 0.5% HEAVY BUPIVACAINE + FENTANYL 25 MCG ON NEWBORN APGAR SCORE BORN TO TERM GESTATION MOTHER BY LOWER SEGMENT CESAREAN SECTION (LSCS) UNDER SUBARACHNOID BLOCK — Akshay Muralidhar, A. Ali, et al. · Asian Journal of Pharmaceutical and Clinical Research (2025) | TGRS Research Map | TGRS