Intracranial infectious complications in patients with combined traumatic brain injury

Aim . To describe the structure of infectious complications and determine the risk of their formation in patients with combined TBI. Material and methods . The study was conducted at the Department of Neurosurgery and Combined Trauma of the Avicenna Tajik State Medical University at the State Medical Centre “Shifobakhsh” from 2020 to 2024. Participants were included according to the following criteria: hospitalisation in a national medical institution in the first 72 hours after TBI, age between 18 and 75 years, and stay in the intensive care unit (ICU) for more than 48 hours. A total of 124 patients with TBI were included. Research results . The acute phase of TBI is characterized by a significant prevalence of intracranial infectious complications, observed in 16% of cases. The most common infectious complication was meningitis, found in 18.7% of patients. The highest frequency of infectious complications was found in patients with category 4-8 intracranial injuries. Conclusion . Combined traumatic brain injury is associated with a high incidence of infectious complications, which were detected in 18.6% of study participants.