BNT162b2 mRNA vaccination affects the gut microbiome composition of patients with follicular lymphoma and chronic lymphocytic leukemia
Taken together, our findings reveal the effect of the BNT162b2 vaccine in shaping the microbiome composition in CLL and FL patients, despite receiving treatment for their underlying active disease, and highlight the importance of a comprehensive analysis of the immunome and microbiome profiling to understand immune function in these cohorts of patients.
Authors
- Angelo Curtopelle (ORCID: https://orcid.org/0000-0003-1648-7979)
- Gaia Vertillo Aluisio (ORCID: https://orcid.org/0000-0003-4534-4176)
- Daniela Cambria (ORCID: https://orcid.org/0000-0003-0753-5174)
- Cirino Botta (ORCID: https://orcid.org/0000-0002-1522-4504)
- Alessandra Romano (ORCID: https://orcid.org/0000-0002-6333-4433)
- Grete Francesca Privitera (ORCID: https://orcid.org/0000-0003-1807-4780)
- Francesco Di Raimondo (ORCID: https://orcid.org/0000-0002-7749-0293)
- Annalisa Chiarenza (ORCID: https://orcid.org/0000-0002-8759-4854)
- Anna Maria Corsale (ORCID: https://orcid.org/0000-0002-2541-4619)
- Sara Marino (ORCID: https://orcid.org/0000-0003-1332-5608)
- Nunziatina Laura Parrinello (ORCID: https://orcid.org/0000-0002-9978-2908)
- Maria Santagati (ORCID: https://orcid.org/0000-0003-1491-4973)
- Enrico La Spina (ORCID: https://orcid.org/0000-0002-8483-4680)
- Gaetano Isola (ORCID: https://orcid.org/0000-0003-4267-6992)
- MojtabaShekarkar Azgomi
Institutions
- University of Catania (IT)
- Policlinico Universitario di Catania (IT)
- University of Palermo (IT)
Publication Details
- Journal
- Biomarker Research
- Published
- 2025-02-10
- DOI
- https://doi.org/10.1186/s40364-025-00734-w
- Citations
- 2
- Primary Topic
- Microscopic Colitis
- Type
- article
- Field-Weighted Citation Impact
- 2.71
Funders
- Università di Catania