Effects of proton pump inhibitors on gastrointestinal bleeding and cardiovascular outcomes in myocardial infarction patients treated with DAPT
In real-world data from a large study of East Asian patients with AMI undergoing PCI and maintaining DAPT, PPI use significantly reduced the risk of major gastrointestinal bleeding without increasing ischaemic events, irrespective of bleeding risk or type of P2Y<sub>12</sub> inhibitor. (ClinicalTrials.gov: NCT06241833).
Authors
- Joo Myung Lee (ORCID: https://orcid.org/0000-0002-2178-4014)
- Hye‐Jeong Park (ORCID: https://orcid.org/0000-0001-8243-079X)
- Ki Hong Choi (ORCID: https://orcid.org/0000-0001-7511-9581)
- Danbee Kang (ORCID: https://orcid.org/0000-0003-0244-7714)
- Seung‐Hyuk Choi (ORCID: https://orcid.org/0000-0002-0304-6317)
- Jeong Hoon Yang (ORCID: https://orcid.org/0000-0001-8138-1367)
- Jihye Heo (ORCID: https://orcid.org/0009-0006-3975-2973)
- Young Bin Song (ORCID: https://orcid.org/0000-0003-3986-9152)
- Juhee Cho (ORCID: https://orcid.org/0000-0001-9081-0266)
- Hyeon‐Cheol Gwon (ORCID: https://orcid.org/0000-0002-4902-5634)
- Taek Kyu Park (ORCID: https://orcid.org/0000-0003-1440-3583)
- Joo‐Yong Hahn (ORCID: https://orcid.org/0000-0002-4412-377X)
Institutions
- Samsung Medical Center (KR)
- Sungkyunkwan University (KR)
Publication Details
- Journal
- EuroIntervention
- Published
- 2025-02-01
- DOI
- https://doi.org/10.4244/eij-d-24-00673
- Citations
- 4
- Primary Topic
- Antiplatelet Therapy and Cardiovascular Diseases
- Type
- article
- Field-Weighted Citation Impact
- 5.55