Evaluation of Quality and Bone Microarchitecture Alterations in Osteopetrosis Patients: Assessed by HR-PQCT
Compared with healthy controls, OPT patients presented with denser trabecular bone, thicker but looser cortical bone, unique bone patterns, and skeletal heterogeneity. These results provide new insights into bone alterations in OPT patients.
Authors
- Xiaoping Xing (ORCID: https://orcid.org/0000-0002-2759-5177)
- Weibo Xia (ORCID: https://orcid.org/0000-0001-7768-5536)
- Yan Jiang (ORCID: https://orcid.org/0000-0003-4434-3462)
- Ruizhi Jiajue (ORCID: https://orcid.org/0000-0002-3796-8440)
- Yushuo Wu
- Xuan Qi (ORCID: https://orcid.org/0000-0001-9441-0841)
- Xiang Li (ORCID: https://orcid.org/0000-0003-1625-5748)
- Mei Li (ORCID: https://orcid.org/0000-0001-8634-2252)
- Li Zhang (ORCID: https://orcid.org/0000-0002-2640-5837)
- Ou Wang (ORCID: https://orcid.org/0000-0002-0395-8789)
- Yue Chi (ORCID: https://orcid.org/0009-0002-7337-9982)
- Qianqian Pang (ORCID: https://orcid.org/0000-0002-4028-5560)
- Lijia Cui (ORCID: https://orcid.org/0000-0002-9929-340X)
- Ruotong Zhou
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking Union Medical College Hospital (CN)
Publication Details
- Journal
- The Journal of Clinical Endocrinology & Metabolism
- Published
- 2025-02-11
- DOI
- https://doi.org/10.1210/clinem/dgaf084
- Primary Topic
- Bone Metabolism and Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Key Research and Development Program of China
- High-level Hospital Construction Project of Guangdong Provincial People's Hospital
- Chinese Academy of Medical Sciences Initiative for Innovative Medicine