Neuropeptide S and its receptor aggravated asthma via TFEB dependent autophagy in bronchial epithelial cells
NPS-NPSR exacerbated asthma by regulating the TFEB-autophagy axis in airway epithelial injury, which may be a potential target for asthma therapy.
Authors
- Gen Yan (ORCID: https://orcid.org/0000-0001-9652-9651)
- Xiangcen Liu
- Xiaorun Zhai
- Peng Zhao (ORCID: https://orcid.org/0000-0003-0899-7303)
- Yunjuan Nie (ORCID: https://orcid.org/0000-0002-6167-4258)
- Zhixu Wang (ORCID: https://orcid.org/0000-0002-1633-6313)
- Jian Li (ORCID: https://orcid.org/0000-0001-7953-8230)
- Li Xu (ORCID: https://orcid.org/0000-0001-6875-9396)
- Ying-Hua Xuan
- Tingting Mei (ORCID: https://orcid.org/0000-0001-8983-0059)
- Aijuan Sun
Institutions
- Jiangnan University (CN)
- Soochow University (CN)
- Second Affiliated Hospital of Soochow University (CN)
- Wuxi People's Hospital (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Respiratory Research
- Published
- 2025-02-10
- DOI
- https://doi.org/10.1186/s12931-025-03125-9
- Citations
- 1
- Primary Topic
- Antimicrobial Peptides and Activities
- Type
- article
- Field-Weighted Citation Impact
- 1.18
Funders
- National Natural Science Foundation of China
- China Postdoctoral Science Foundation
- Government of Jiangsu Province
- Natural Science Foundation of Jiangsu Province
- Postdoctoral Science Foundation of Jiangsu Province