A stratified two-stage tumor molecular profiling algorithm to identify clinically actionable molecular alterations in pancreatic cancer
Stratified two-stage TMP reliably identifies actionable alterations in PC patients, with potential therapeutic benefit. The proposed TMP algorithm might be as effective, yet more feasible and economic compared with comprehensive upfront testing.
Authors
- Ralph Fritsch (ORCID: https://orcid.org/0000-0001-9639-3213)
- Markus Rechsteiner
- Chantal Pauli (ORCID: https://orcid.org/0000-0001-9621-8511)
- Antonia Töpfer
- Achim Weber (ORCID: https://orcid.org/0000-0003-0073-3637)
- Martin Zoche (ORCID: https://orcid.org/0000-0002-0421-7229)
- Clelia Pistoni (ORCID: https://orcid.org/0000-0002-2644-8837)
- Saskia Hussung (ORCID: https://orcid.org/0000-0001-7987-0065)
- Christian Britschgi (ORCID: https://orcid.org/0000-0001-8831-1564)
- Dilara Akhoundova (ORCID: https://orcid.org/0000-0003-1639-3059)
- Holger Moch (ORCID: https://orcid.org/0000-0002-7986-2839)
- BC Pestalozzi
- Daniela Lenggenhager (ORCID: https://orcid.org/0000-0002-5382-9854)
Institutions
- University of Bern (CH)
- University of Zurich (CH)
- University Hospital of Bern (CH)
- University Hospital of Zurich (CH)
Publication Details
- Journal
- ESMO Gastrointestinal Oncology
- Published
- 2025-02-10
- DOI
- https://doi.org/10.1016/j.esmogo.2025.100134
- Primary Topic
- Pancreatic and Hepatic Oncology Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Stiftung Max und Sophielène Iten-Kohaut