Efficacy of Inactivated Bivalent SARS-CoV-2 Vaccines Targeting Ancestral Strain (ERAGEM), Delta, and Omicron Variants
The bivalent inactivated vaccines demonstrated strong immunogenicity and complete protection against severe disease in preclinical models. These findings indicate the potential of bivalent vaccine strategies in addressing antigenic diversity and preparing for future pandemics caused by rapidly evolving pathogens.
Authors
- Hazel Yetişkin (ORCID: https://orcid.org/0000-0003-0813-791X)
- Esma Eren (ORCID: https://orcid.org/0000-0002-2712-9694)
- Muhammet Ali Uygut (ORCID: https://orcid.org/0000-0002-8794-341X)
- Yesari Eröksüz (ORCID: https://orcid.org/0000-0001-5962-8810)
- Aykut Özdarendeli (ORCID: https://orcid.org/0000-0002-6950-8545)
- Merve Gökşin Karaaslan (ORCID: https://orcid.org/0000-0003-2645-808X)
- İ̇lhami Çelik (ORCID: https://orcid.org/0000-0002-2604-3776)
- Shaikh Terkıs Islam Pavel (ORCID: https://orcid.org/0000-0002-7178-0943)
- Gülay Korukluoğlu (ORCID: https://orcid.org/0000-0001-7625-6350)
- Ateş Kara (ORCID: https://orcid.org/0000-0002-1654-3232)
- B. S. Kaplan (ORCID: https://orcid.org/0000-0002-2029-6270)
Institutions
- Fırat University (TR)
- University of Health Science (KH)
- Hacettepe University Hospital (TR)
- Research & Development Institute (US)
- Sağlık Bilimleri Üniversitesi (TR)
- Kayser (Italy) (IT)
- Erciyes University (TR)
Publication Details
- Journal
- Vaccines
- Published
- 2025-02-10
- DOI
- https://doi.org/10.3390/vaccines13020169
- Primary Topic
- SARS-CoV-2 and COVID-19 Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Yükseköğretim Kurulu