Reproducibility of a mathematical model of the neural regulation of phasic contractions and slow waves in the distal stomach

A mathematical model of neural regulation of distal gastric interstitial cells of Cajal and smooth muscle cells was developed by Athavale et al. (2023). The model incorporated five cellular mechanisms, of which four were inhibitory and one was excitatory. The membrane potential oscillations due to phasic slow wave activity, and resulting active tension generation were simulated by the model. Neural regulation input was determined by the frequency of electrical field stimulation, and the steady-state slow wave and contraction response to this stimulation was simulated. This article appraises the reproducibility of results from Athavale et al. (2023) using the provided model analysis code. Scripts for plotting model analysis results were modified to ensure operability on Unix and Windows platforms and to ease the interpretability of figures in the absence of figure captions.