Application and effect evaluation of microsurgical resection combined with intensity-modulated radiation therapy in the treatment of intracranial solitary fibrous tumor/hemangiopericytoma

Intracranial solitary fibrous tumor (SFT) and hemangiopericytoma (HPC) are rare mesenchymal tumors with significant vascularization, often misdiagnosed as meningiomas. Surgical resection is the primary treatment, with postoperative radiotherapy increasingly recognized for its role in improving recurrence-free survival. However, standard radiotherapy regimens remain undefined. We retrospectively analyzed clinical data from 12 patients diagnosed with SFT/HPC who underwent surgical resection and postoperative intensity-modulated radiotherapy. Clinical information, imaging findings, treatment methods, and outcomes were reviewed. Surgical resection achieved complete or subtotal tumor removal in all cases. Postoperative radiotherapy was administered to 8 patients. During follow-up, 3 patients experienced tumor recurrence, necessitating reoperation, while 1 patient died due to complications. Those who received radiotherapy showed a trend towards reduced recurrence. Surgical resection remains the cornerstone of SFT/HPC treatment, with adjuvant radiotherapy potentially improving outcomes. However, individualized treatment strategies and long-term follow-up are crucial due to the tumor's propensity for recurrence. Further research is needed to optimize treatment approaches and enhance patient survival and quality of life.