Changes in Aqueous Humor Cytokine Profile Following Intravitreal Brolucizumab Injection
Our study demonstrated a significant increase in aqueous pro-inflammatory cytokines in eyes treated with intravitreal brolucizumab. Nearly all eyes studied showed no clinical signs of intraocular inflammation. The results suggested that type IV cell-mediated hypersensitivity could play a role in IOI following intravitreal brolucizumab injection.
Authors
- Wijak Kongwattananon (ORCID: https://orcid.org/0000-0002-3459-7197)
- Varis Ruamviboonsuk (ORCID: https://orcid.org/0000-0003-4531-1729)
- Natthaya Chuaypen (ORCID: https://orcid.org/0000-0002-5415-510X)
Institutions
- Thai Red Cross Society (TH)
- Chulalongkorn University (TH)
- King Chulalongkorn Memorial Hospital (TH)
Publication Details
- Journal
- Clinical ophthalmology
- Published
- 2025-02-01
- DOI
- https://doi.org/10.2147/opth.s504956
- Citations
- 1
- Primary Topic
- Retinal Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.71
Funders
- Chulalongkorn University
- Faculty of Medicine, Chulalongkorn University