Comprehensive Characterization and Bioactivity Assessment of Titanium Dioxide Nanoparticles Synthesized Using <i>Chrysanthemum indicum</i> Leaf Extract
Bionanotechnology is the synthesis of environmentally friendly, biosynthetic nanomaterials by combining nanotechnology and biotechnology. Chrysanthemum indicum leaf extract in aqueous medium was used in the presented research work to produce titanium dioxide (TiO<sub>2</sub>) nanoparticles using a dependable and environmentally friendly method. The TiO<sub>2</sub> nanoparticles derived from C. indicum were examined using scanning electron microscopy (SEM) and Fourier-transform infrared spectroscopy. The diesel degradation activity of the TiO<sub>2</sub> was evaluated, showing a significant reduction in diesel concentration (8%) after a 10-day incubation period. Furthermore, TiO<sub>2</sub>'s hemolytic, antidiabetic, anti-inflammatory, and antioxidant properties were highlighted. Cubical-shaped nanoparticles with an even distribution were found by SEM analysis. When compared to standard drugs, the biosynthesized TiO<sub>2</sub> nanoparticles demonstrated hemolytic potential, anti-inflammatory (albumin denaturation assay), antidiabetic, and antioxidant (2,2-diphenyl-1-picrylhydrazyl assay) properties. These results imply that TiO<sub>2</sub> nanoparticles function as advantageous biological agents and are crucial to the bioremediation process. Due to the great potential of TiO<sub>2</sub> nanoparticles, the notable characteristics of biosynthesized TiO<sub>2</sub> nanoparticles suggest their potential useful applications in the biodegradation field in the future.
Authors
- Syeda Izma Makhdoom (ORCID: https://orcid.org/0000-0002-9978-1067)
- M. ALHARBI (ORCID: https://orcid.org/0009-0007-7998-0222)
- Abdullah F. Alasmari (ORCID: https://orcid.org/0000-0001-7569-4287)
- Ayaz Ali Khan (ORCID: https://orcid.org/0000-0002-9274-2620)
- Tariq Aziz (ORCID: https://orcid.org/0000-0003-0905-8076)
- Muhammad Waseem (ORCID: https://orcid.org/0000-0001-7135-9529)
- Maida Salah Ud Din (ORCID: https://orcid.org/0009-0005-5248-0928)
- Muhammad Naveed (ORCID: https://orcid.org/0000-0002-6935-8479)
Institutions
- University of Central Punjab (PK)
- University of Ioannina (GR)
- King Saud University (SA)
- University of Malakand (PK)
Publication Details
- Journal
- Chemistry & Biodiversity
- Published
- 2025-02-11
- DOI
- https://doi.org/10.1002/cbdv.202500244
- Citations
- 8
- Primary Topic
- Nanoparticles: synthesis and applications
- Type
- article
- Field-Weighted Citation Impact
- 4.14
Funders
- King Saud University