Clinical Features and Prognosis of Double-Positive Anti-MDA5 and Anti-CCP Antibodies in Dermatomyositis: A Retrospective Study

More than half of the patients with MDA5+/CCP+ DM may present with arthritis as one of the initial symptoms. They may also have an increased risk of malignancy. For MDA5+ DM patients with positive anti-CCP antibodies, thorough screening for tumors is crucial to guide treatment and improve prognosis.

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Publication Details

Journal
Journal of Inflammation Research
Published
2025-02-01
DOI
https://doi.org/10.2147/jir.s503120
Primary Topic
Inflammatory Myopathies and Dermatomyositis
Type
article
Field-Weighted Citation Impact
0.00

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article

Clinical Features and Prognosis of Double-Positive Anti-MDA5 and Anti-CCP Antibodies in Dermatomyositis: A Retrospective Study

Yongpeng Ge, Longyang Zhu, Guochun Wang, Xinshui Xu et al.
Journal of Inflammation Research
Inflammatory Myopathies and Dermatomyositis
article

Clinical Features and Prognosis of Double-Positive Anti-MDA5 and Anti-CCP Antibodies in Dermatomyositis: A Retrospective Study

Yongpeng Ge, Longyang Zhu, Guochun Wang, Xinshui Xu, Sizhao Li
article en

Abstract

More than half of the patients with MDA5+/CCP+ DM may present with arthritis as one of the initial symptoms. They may also have an increased risk of malignancy. For MDA5+ DM patients with positive anti-CCP antibodies, thorough screening for tumors is crucial to guide treatment and improve prognosis.

Journal of Inflammation ResearchVol. Volume 18
Peking University (CN), China-Japan Friendship Hospital (CN), Hainan Medical University (CN)
China-Japan Friendship Hospital
Good health and well-being
Openalex Percentile: Top 96%
Inflammatory Myopathies and Dermatomyositis
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Clinical Features and Prognosis of Double-Positive Anti-MDA5 and Anti-CCP Antibodies in Dermatomyositis: A Retrospective Study — Yongpeng Ge, Longyang Zhu, et al. · Journal of Inflammation Research (2025) | TGRS Research Map | TGRS