Pyrvinium Pamoate Synergizes with Azoles in vitro and in vivo to Exert Antifungal Efficacy Against Candida auris and Other Candida Species
Combining PP with azoles represents a promising approach to effectively disrupting the growth of azole-resistant <i>C. auris</i> and other <i>Candida spp</i>. such that it may be a promising anti-<i>Candida</i> therapeutic option.
Authors
- Heng Zhang (ORCID: https://orcid.org/0009-0007-3240-7867)
- Gang Li (ORCID: https://orcid.org/0000-0002-3981-2239)
- Jingwen Tan (ORCID: https://orcid.org/0000-0002-2166-2682)
- Jing Hu (ORCID: https://orcid.org/0009-0007-8446-0862)
- Jinqing Zhang (ORCID: https://orcid.org/0000-0002-5644-3076)
- Yizheng Zhou
Institutions
- Tongji University (CN)
- Yangtze University (CN)
- Capital Medical University (CN)
- Beijing Chao-Yang Hospital, Capital Medical University (CN)
- Shanghai Skin Disease Hospital (CN)
Publication Details
- Journal
- Infection and Drug Resistance
- Published
- 2025-02-01
- DOI
- https://doi.org/10.2147/idr.s497929
- Citations
- 3
- Primary Topic
- Antifungal resistance and susceptibility
- Type
- article
- Field-Weighted Citation Impact
- 2.79
Funders
- Tongji University
- State Key Laboratory of Virology