Deciphering CSU pathogenesis: Network toxicologyand molecular dynamics of DOTP exposure

This study clarifies the potential molecular mechanisms of DOTP-induced CSU and underscores the efficacy of network toxicology, molecular docking, and molecular dynamics simulations in assessing the toxicity of food and environmental pollutants and their related molecular biological mechanisms. These findings offer new insights for future research, enhance our comprehension of the potential health impacts of food and environmental pollutants, and establish a scientific foundation for the development of prevention and treatment strategies.

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Publication Details

Journal
Ecotoxicology and Environmental Safety
Published
2025-02-01
DOI
https://doi.org/10.1016/j.ecoenv.2025.117864
Citations
19
Primary Topic
Radiopharmaceutical Chemistry and Applications
Type
article
Field-Weighted Citation Impact
25.84

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article

Deciphering CSU pathogenesis: Network toxicologyand molecular dynamics of DOTP exposure

Cui Guo, Jing Guo, Fang Cao
19 citations
Ecotoxicology and Environmental Safety
Radiopharmaceutical Chemistry and Applications
25.84
article

Deciphering CSU pathogenesis: Network toxicologyand molecular dynamics of DOTP exposure

Cui Guo, Jing Guo, Fang Cao
article en
19 citations

Abstract

This study clarifies the potential molecular mechanisms of DOTP-induced CSU and underscores the efficacy of network toxicology, molecular docking, and molecular dynamics simulations in assessing the toxicity of food and environmental pollutants and their related molecular biological mechanisms. These findings offer new insights for future research, enhance our comprehension of the potential health impacts of food and environmental pollutants, and establish a scientific foundation for the development of prevention and treatment strategies.

Ecotoxicology and Environmental SafetyVol. 291
Chengdu University of Traditional Chinese Medicine (CN)
National Natural Science Foundation of China
Zero hunger
Openalex Percentile: Top 0%
Radiopharmaceutical Chemistry and Applications
25.84
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