Nanocarrier-Mediated dermal drug delivery for skin disorders

Skin diseases have a profound effect on the overall well-being of affected individuals, often associated with physical and mental anguish as well as social stigma. Traditional methods of treatment lack effectiveness in dealing with skin disorders and suffer from several limitations such as long treatment duration and high incidence of systemic side effects. Nanocarrier-based dermal drug delivery platforms help mitigate several of these limitations due to their site-specific delivery and superior retention at the target site, leading to minimization of off-target adverse events. Additionally, they bestow several theranostic advantages due to improved skin penetration as well as better control over drug release rates. This article advocates for the adoption of nanocarrier-based dermal drug delivery strategies as a solution to the shortcomings of conventional methods offering more effective, targeted, and patient-friendly treatments for several skin disorders such as psoriasis, atopic dermatitis and skin cancer.