Disability profile of childhood and adolescent leprosy: A 10-year retrospective record-based study at tertiary care center

Leprosy is a chronic granulomatous infectious disease in tropical countries. Children and adolescent with leprosy pose a great burden in society. Disability which develops in children and adolescent, have negative effect on social, personal and academic life. To break the chain of transmission in these patients we must find lacunae in disease development in those patients. It is a retrospective record-based study conducted at tertiary care hospital. Case records for the period of 10 years (August 2010 to August 2020) were examined. All confirmed cases of leprosy who developed disability before, during and after taking MDT, were graded according to WHO disability grading (WHO 1988). Out of 568 patients diagnosed with leprosy, 61 (10.7%) patients developed disability, out of which 20 (32.78%) patients belonged to <15 years and 41(67.21%) belonged to 15-19 years. Male:Female ratio 2:1. 25 (41%) patients had positive family history and 20 (32.8%) patients had positive Slit skin smear examination for Acid fast bacilli. 25 (41%) patients had Multibacillary leprosy and 36 (59%) patients had Paucibacillary leprosy. 8 (13.11%) patients had type-2 lepra reaction while 6 (9.8%) patients had type-1 lepra reaction. Total 6 (9.8%) patients developed disability, out of which 2 (3.2%) patients had Grade 2 disability. Leprosy in children is more important as it has great impact on child as well as family. Hence, regular close monitoring of child and adolescent with leprosy is required to avoid development of disabilities.

Authors

Institutions

Publication Details

Journal
IP Indian Journal of Clinical and Experimental Dermatology
Published
2025-02-08
DOI
https://doi.org/10.18231/j.ijced.2025.012
Primary Topic
Leprosy Research and Treatment
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Disability profile of childhood and adolescent leprosy: A 10-year retrospective record-based study at tertiary care center

Khushbu R. Modi, Niraj Dhinoja, Neela Patel, Avanita Solanki et al.
IP Indian Journal of Clinical and Experimental Dermatology
Leprosy Research and Treatment
article

Disability profile of childhood and adolescent leprosy: A 10-year retrospective record-based study at tertiary care center

Khushbu R. Modi, Niraj Dhinoja, Neela Patel, Avanita Solanki, Twinkle C Rangnani
article en

Abstract

Leprosy is a chronic granulomatous infectious disease in tropical countries. Children and adolescent with leprosy pose a great burden in society. Disability which develops in children and adolescent, have negative effect on social, personal and academic life. To break the chain of transmission in these patients we must find lacunae in disease development in those patients. It is a retrospective record-based study conducted at tertiary care hospital. Case records for the period of 10 years (August 2010 to August 2020) were examined. All confirmed cases of leprosy who developed disability before, during and after taking MDT, were graded according to WHO disability grading (WHO 1988). Out of 568 patients diagnosed with leprosy, 61 (10.7%) patients developed disability, out of which 20 (32.78%) patients belonged to <15 years and 41(67.21%) belonged to 15-19 years. Male:Female ratio 2:1. 25 (41%) patients had positive family history and 20 (32.8%) patients had positive Slit skin smear examination for Acid fast bacilli. 25 (41%) patients had Multibacillary leprosy and 36 (59%) patients had Paucibacillary leprosy. 8 (13.11%) patients had type-2 lepra reaction while 6 (9.8%) patients had type-1 lepra reaction. Total 6 (9.8%) patients developed disability, out of which 2 (3.2%) patients had Grade 2 disability. Leprosy in children is more important as it has great impact on child as well as family. Hence, regular close monitoring of child and adolescent with leprosy is required to avoid development of disabilities.

IP Indian Journal of Clinical and Experimental DermatologyVol. 11(1)
Shree Krishna Hospital (IN)
Openalex Percentile: Top 96%
Leprosy Research and Treatment
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.