Analytico-empirical silhouette of concurrent disorders allied to psoriasis with liaison to biochemical parameters in patients attending a tertiary care hospital

Psoriasis is a ubiquitous ailment seen in day to day Dermatology practice. Multitude of stipulations have lead to discern pathogenesis of the disease reverberating it as a systemic disease with cutaneous manifestations being fraction of spectrum. The aim of the study was to analyse comorbidities associated with psoriasis, with it’s consortium to severity of psoriasis. Cross-sectional, descriptive study undertaken in a tertiary care centre after taking informed consent from the patients. The study was attained over a period of 18 months. Patients with diagnosed psoriasis were evaluated for relevant demographic and biochemical parameters according to pre-set proforma. Sample size was calculated according to Cochrane formula. Single sample. Paired sample t test and Chi square test were used to test statistical significance and p< 0.05 was considered statistically significant. 66 patients attending outdoor patients ward of Burdwan Medical College and Hospital were evaluated. Prevalence of comorbidities were assessed. Mild but significant correlation was found between elevated serum triglyceride and lipid levels with severity of psoriasis. No association was found between increased serum uric acid level and psoriatic arthritis, no association was found between severity of psoriasis and blood glucose levels. Since its already opined that the systemic inflammatory nature of the disease can lead to increased incidence of metabolic syndrome and lipid profile abnormalities as substantiated by western studies, it becomes irrefutable for the treating Dermatologists to be more aggressive to delve deeper and approach holistically towards treatment of the disease . Psoriasis is a systemic condition rather being a mere cutaneous disorder, comprehensive knowledge of the disease aids in curbing significant morbidity.