Sociogenomics: Gene-environment Interactions in Enamel Defects

Sociogenomics, an interdisciplinary field at the intersection of genomics and social sciences, offers a unique lens to understand the complex interplay between genetic predispositions and social/environmental influences on human health. While hypomineralisation has traditionally been studied from a biological standpoint, recent advancements in sociogenomics shed light on the significance of social determinants in shaping its impact. Sociogenomic approaches advocate for an integrative perspective, acknowledging the contribution of social determinants in modulating the expression and severity of hypomineralisation. The present short communication explores the emerging connections between sociogenomics and dental hypomineralisation.