Can muscle synergies shed light on the mechanisms underlying motor gains in response to robot-assisted gait training in children with cerebral palsy?
Gait impairments in children with CP were associated with muscle synergies that deviated from normative. Participants who demonstrated the most substantial improvements in clinical scores following RGT exhibited multiple changes in the muscle synergies. However, no statistically significant correlations were identified at the group level. Future studies relying on larger datasets are needed to further investigate this observation and potential underlying mechanisms.
Authors
- Stefano Sapienza (ORCID: https://orcid.org/0000-0002-0917-6454)
- Gloria Vergara-Díaz (ORCID: https://orcid.org/0000-0003-1072-1322)
- Giacomo Severini (ORCID: https://orcid.org/0000-0002-2289-9331)
- Jean‐François Daneault (ORCID: https://orcid.org/0000-0002-8530-1827)
- Vincent C. K. Cheung (ORCID: https://orcid.org/0000-0002-6031-7320)
- Eric Fabara (ORCID: https://orcid.org/0000-0001-9983-0474)
- Paolo Bonato (ORCID: https://orcid.org/0000-0002-1818-1714)
- Catherine Adans-Dester (ORCID: https://orcid.org/0000-0001-6816-0586)
- Donna Nimec
- Carmen Echevarría Ruiz de Vargas
Institutions
- University College Dublin (IE)
- Rutgers, The State University of New Jersey (US)
- Harvard University (US)
- Chinese University of Hong Kong (HK)
- University of Luxembourg (LU)
- Spaulding Rehabilitation Hospital (US)
- Luxembourg Institute of Health (LU)
- Hospital Universitario Virgen del Rocío (ES)
Publication Details
- Journal
- Journal of NeuroEngineering and Rehabilitation
- Published
- 2025-02-07
- DOI
- https://doi.org/10.1186/s12984-025-01550-x
- Citations
- 4
- Primary Topic
- Cerebral Palsy and Movement Disorders
- Type
- article
- Field-Weighted Citation Impact
- 5.88
Funders
- Fundación Alfonso Martín Escudero
- Real Colegio Complutense
- Peabody Foundation
- Chinese University of Hong Kong
- Foundation for Physical Medicine and Rehabilitation