Efficacy and safety of intravenous alteplase for unknown onset stroke on prior antiplatelet therapy: Post hoc analysis of the EOS individual participant data

Alteplase has consistent efficacy regardless of prior APT in patients with unknown onset stroke. In addition, prior APT does not significantly increase the risk of sICH or mortality.

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Publication Details

Journal
International Journal of Stroke
Published
2025-02-08
DOI
https://doi.org/10.1177/17474930251322034
Citations
1
Primary Topic
Acute Ischemic Stroke Management
Type
article
Field-Weighted Citation Impact
1.35
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article

Efficacy and safety of intravenous alteplase for unknown onset stroke on prior antiplatelet therapy: Post hoc analysis of the EOS individual participant data

Yuma Shiomi, Ona Wu, Mayumi Fukuda‐Doi, Götz Thomalla et al.
1 citations
International Journal of Stroke
Acute Ischemic Stroke Management
1.35
article

Efficacy and safety of intravenous alteplase for unknown onset stroke on prior antiplatelet therapy: Post hoc analysis of the EOS individual participant data

Yuma Shiomi, Ona Wu, Mayumi Fukuda‐Doi, Götz Thomalla, Sohei Yoshimura, Ḱazunori Toyoda, Naruhiko Kamogawa, Manabu Inoue, Geoffrey Alan Donnan, Masatoshi Koga, Märit Jensen, Jin Nakahara, Stephen M. Davis, Peter A. Ringleb, Henry Ma, Christian Gerloff, Lee H. Schwamm, Kaori Miwa
article en
1 citations

Abstract

Alteplase has consistent efficacy regardless of prior APT in patients with unknown onset stroke. In addition, prior APT does not significantly increase the risk of sICH or mortality.

International Journal of StrokeVol. 20(6)
The Royal Melbourne Hospital (AU), Universität Hamburg (DE), The University of Melbourne (AU), Keio University (JP), Heidelberg University (DE), Yale University (US), Massachusetts General Hospital (US), University Medical Center Hamburg-Eppendorf (DE), National Cerebral and Cardiovascular Center (JP), Athinoula A. Martinos Center for Biomedical Imaging (US), Klinik und Poliklinik für Neurologie (DE), Monash University (AU)
Good health and well-being
Openalex Percentile: Top 23%
Acute Ischemic Stroke Management
1.35
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