Designing a meditation module to affect etiological and preventive factors in primary hypertensive patients—A pilot study

The aim of the present pilot study is to design, validate, and check the feasibility and efficacy of the designed meditation module on etiological and preventive factors in primary hypertensive patients (PHP). The systematic and detailed meditation module was formulated to prevent the complications of hypertension. The designed module was validated by 5 subject experts in the field of complementary and alternative therapy and research. Content Validity Ratio (CVR), Average Congruency Percentage (ACP), and Content Validity Index were calculated. The intervention was given for 5 days a week for 4 weeks, to 9 PHP to check the feasibility and the efficacy of the module by analyzing biochemical and psychological parameters. A randomized controlled trial is planned ahead with this module as intervention. The designed meditation module had 19 concepts with CVR >0.49 and ACP > 90% which were retained, 2 were modified (CVR 0.6, ACP 80) and 1 was deleted as CVR was <0.49 and ACP < 70%. The feasibility test mean was 93.33 ± 8.66 and the efficacy was tested by increase in the brain-derived neurotrophic factor (BDNF) (p = 0.022) and decrease in anxiety (p = 0.022) and perceived stress (p = 0.016), improvement in emotional quotient (p = 0.011), mental state (p = 0.044), quality of sleep (p = 0.001), quality of life (p = 0.011), and happiness state (p = 0.003). The designed meditation module was found valid by the experts, feasible to patients, and efficient in improving biochemical and psychological parameters among PHP to affect the hypertensive etiological factors and check the progress and complications of the disorder. Trial Registration: CTRI/2022/09/045421.