Researcher views on returning results from multi-omics data to research participants: insights from The Molecular Transducers of Physical Activity Consortium (MoTrPAC) Study
Overall, researchers expressed positive attitudes toward multi-omic return of results in principle, particularly if medically actionable. However, competing ethical considerations, logistical constraints, and need for more external guidance were raised as key implementation concerns. Future studies should consider views and experiences of other relevant stakeholders, specifically clinical genomics professionals and study participants, regarding the clinical utility of multi-omics information and multi-omics results return.
Authors
- Kelly E. Ormond (ORCID: https://orcid.org/0000-0002-1033-0818)
- Caroline Stanclift (ORCID: https://orcid.org/0000-0002-9208-8550)
- Jennefer N. Carter (ORCID: https://orcid.org/0000-0003-0830-3535)
- Chloe M. Reuter (ORCID: https://orcid.org/0000-0002-0429-9922)
- Matthew Thomas Wheeler (ORCID: https://orcid.org/0000-0001-8721-3022)
- Maléne E. Lindholm (ORCID: https://orcid.org/0000-0002-5763-7833)
- Kathleen Murphy
Institutions
- ETH Zurich (CH)
- Stanford University (US)
Publication Details
- Journal
- BMC Medical Ethics
- Published
- 2025-02-07
- DOI
- https://doi.org/10.1186/s12910-025-01174-9
- Citations
- 3
- Primary Topic
- Health, Environment, Cognitive Aging
- Type
- article
- Field-Weighted Citation Impact
- 3.60
Funders
- U.S. Department of Health and Human Services
- National Institutes of Health
- Common Fund