Psychometric properties and meaningful change thresholds for the QOL-E instrument in patients with myelodysplastic neoplasms
The study results demonstrate that the QOL-E is generally fit for purpose to assess treatment effects in populations with LR-MDS and the proposed MWPC thresholds can be used to assess within-patient treatment effect on PROs, as assessed by the QOL-E, in future studies.
Authors
- Esther Natalie Olíva (ORCID: https://orcid.org/0000-0001-9238-5734)
- Roberto Latagliata (ORCID: https://orcid.org/0000-0002-7741-862X)
- Pierre Fenaux (ORCID: https://orcid.org/0000-0002-0468-3553)
- Grazia Sanpaolo
- Giuseppe A. Palumbo (ORCID: https://orcid.org/0000-0003-1859-6319)
- C. Pelligra (ORCID: https://orcid.org/0000-0002-5255-2777)
- Jennifer Lord‐Bessen (ORCID: https://orcid.org/0000-0001-8624-4556)
- Uwe Platzbecker (ORCID: https://orcid.org/0000-0003-1863-3239)
- Massimo Breccia (ORCID: https://orcid.org/0000-0003-1163-6162)
- Valeria Santini (ORCID: https://orcid.org/0000-0002-5439-2172)
- Shien Guo
- Guillermo Garcia-Manero
- Marta Riva
- Aylin Yücel (ORCID: https://orcid.org/0000-0001-5947-062X)
Institutions
- Ithaka Harbors (US)
- The University of Texas MD Anderson Cancer Center (US)
- Université Paris Cité (FR)
- Casa Sollievo della Sofferenza (IT)
- Policlinico Umberto I (IT)
- University of Catania (IT)
- Bristol-Myers Squibb (United States) (US)
- Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda (IT)
- Azienda ospedaliera "Bianchi-Melacrino-Morelli" (IT)
- University Hospital Leipzig (DE)
- Ospedale di Belcolle (IT)
- Hôpital Saint-Louis (FR)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- University of Florence (IT)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-02-07
- DOI
- https://doi.org/10.3389/fonc.2025.1507854
- Citations
- 1
- Primary Topic
- Acute Myeloid Leukemia Research
- Type
- article
- Field-Weighted Citation Impact
- 1.77
Funders
- Bristol-Myers Squibb