Association of metabolic dysfunction‐associated fatty liver disease with white matter hyperintensity and cognitive decline: A longitudinal cohort study
MAFLD was associated with an increased risk of WMH over 4.1 years in middle-aged adults. The hepatic steatosis itself was independently associated with an increased risk of WMH regardless of comorbid metabolic abnormalities. The degree of hepatic steatosis was associated with decreased executive function, especially in non-obese individuals.
Authors
- Hyun Joo Cho
- Ji Hee Yu (ORCID: https://orcid.org/0000-0003-1907-2859)
- Chol Shin (ORCID: https://orcid.org/0000-0002-2928-8576)
- Seung Ku Lee (ORCID: https://orcid.org/0000-0001-5120-5557)
- Da Young Lee
- Ji A Seo (ORCID: https://orcid.org/0000-0002-1927-2618)
- Nan Hee Kim (ORCID: https://orcid.org/0000-0003-4378-520X)
- Inha Jung (ORCID: https://orcid.org/0000-0001-8561-8544)
- So Young Park (ORCID: https://orcid.org/0000-0002-7973-5944)
Institutions
- Korea University (KR)
- Ansan University (KR)
Publication Details
- Journal
- Diabetes Obesity and Metabolism
- Published
- 2025-02-06
- DOI
- https://doi.org/10.1111/dom.16232
- Citations
- 3
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 4.06
Funders
- National Research Foundation
- Korea University
- National Research Foundation of Korea
- National Institutes of Health