Leveraging genomic insights from the neglected malaria parasites P. malariae and P. ovale using selective whole genome amplification (SWGA) approach
SWGA approach implemented here provides a powerful tool for enhancing genomic analysis of these neglected parasites, revealing population diversity, drug resistance markers, and hypervariable regions. This methodology constitutes a transformative tool to surmount the challenges of genomic analysis for neglected malaria parasites and can improve malaria research and control.
Authors
- Jun Cao (ORCID: https://orcid.org/0000-0001-5298-9234)
- Di Liu (ORCID: https://orcid.org/0000-0002-0708-7466)
- Arnab Pain (ORCID: https://orcid.org/0000-0002-1755-2819)
- Yaobao Liu
- Amit Kumar Subudhi (ORCID: https://orcid.org/0000-0002-3079-3705)
- Rohit Satyam (ORCID: https://orcid.org/0000-0002-9311-4992)
- Fathia Ben Rached (ORCID: https://orcid.org/0000-0001-6601-3080)
- Raeece Naeem (ORCID: https://orcid.org/0000-0003-1734-1007)
- Caroline Askonas (ORCID: https://orcid.org/0000-0003-3755-2805)
- Mariah Alawi
- Zenaida Stead (ORCID: https://orcid.org/0000-0001-9380-4961)
- Sara Mfarrej (ORCID: https://orcid.org/0000-0002-6460-8862)
- Chang Li (ORCID: https://orcid.org/0000-0001-8019-3794)
- Sui Xu
- Guoding Zhu
Institutions
- Hokkaido University (JP)
- Sapporo International University (JP)
- Jiangsu Institute of Parasitic Diseases (CN)
- King Abdullah University of Science and Technology (SA)
- Nanjing Medical University (CN)
Publication Details
- Journal
- BMC Genomics
- Published
- 2025-02-07
- DOI
- https://doi.org/10.1186/s12864-025-11292-8
- Citations
- 2
- Primary Topic
- Genomics and Phylogenetic Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.61
Funders
- National Natural Science Foundation of China
- Government of Jiangsu Province
- King Abdullah University of Science and Technology
- Centers for Disease Control and Prevention