Disease-free survival as surrogate for overall survival in esophageal cancer: An individual patient data meta-analysis of neoadjuvant chemotherapy and chemoradiotherapy
DFS is a validated surrogate endpoint for OS in trials evaluating neoadjuvant chemotherapy or chemoradiotherapy in E/GEJ. DFS may be more useful as an endpoint when delays between recurrences and death become larger.
Authors
- Bryan Burmeister (ORCID: https://orcid.org/0000-0001-9927-5650)
- Marc Ychou (ORCID: https://orcid.org/0000-0001-7378-9469)
- Guillaume Piessen (ORCID: https://orcid.org/0000-0001-8243-8310)
- Joel E. Tepper (ORCID: https://orcid.org/0000-0002-8591-4228)
- B. Mark Smithers (ORCID: https://orcid.org/0000-0002-8333-8685)
- Val Gebski (ORCID: https://orcid.org/0000-0001-8748-1844)
- Matthieu Faron (ORCID: https://orcid.org/0000-0003-2331-0792)
- Nicolas Cabrit
- Florent de Vathaire (ORCID: https://orcid.org/0000-0002-8374-9281)
- Jean‐Pierre Pignon (ORCID: https://orcid.org/0000-0003-2047-1582)
- Janine Thomas
- P. Thirion (ORCID: https://orcid.org/0000-0003-4525-1631)
- Jayne F. Tierney (ORCID: https://orcid.org/0000-0002-4734-3014)
- Florian Lordick (ORCID: https://orcid.org/0000-0001-8591-9339)
- D. Williaume
- David Cunningham (ORCID: https://orcid.org/0000-0001-5158-1069)
- Michele Valmasoni (ORCID: https://orcid.org/0000-0002-1462-8275)
- Matthew Nankivell (ORCID: https://orcid.org/0000-0003-3904-2729)
- Johanna van Sandick
- Stefan Michiels (ORCID: https://orcid.org/0000-0002-6963-2968)
- M. Cheugoua-Zanetsie (ORCID: https://orcid.org/0000-0002-9447-4631)
- Simon Law (ORCID: https://orcid.org/0000-0002-6518-5806)
- Magnus Nilsson (ORCID: https://orcid.org/0000-0002-6215-8132)
- Michel Ducreux (ORCID: https://orcid.org/0000-0001-8649-7449)
- Susan G. Urba
- Xavier Paolettí (ORCID: https://orcid.org/0000-0002-1250-0040)
- Jurjen J. Boonstra (ORCID: https://orcid.org/0000-0002-8221-9158)
- Jian Fu (ORCID: https://orcid.org/0000-0002-2680-0394)
- M. Stahl (ORCID: https://orcid.org/0000-0003-0568-4715)
- Kathryn Winter
- Bas P. L. Wijnhoven
- Hong Yang (ORCID: https://orcid.org/0000-0003-1936-3525)
- Déwi Vernerey (ORCID: https://orcid.org/0000-0001-6399-926X)
Institutions
- Centre National de la Recherche Scientifique (FR)
- Karolinska University Hospital (SE)
- University of Padua (IT)
- Inserm (FR)
- Sun Yat-sen University (CN)
- Trinity College Dublin (IE)
- Université de Lille (FR)
- Université Paris-Saclay (FR)
- Leiden University Medical Center (NL)
- Princess Alexandra Hospital (AU)
- Institut Gustave Roussy (FR)
- Erasmus MC (NL)
- Centre de recherche en Epidémiologie et Santé des Populations (FR)
- Centre Eugène Marquis (FR)
- Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital (NL)
- Kliniken Essen-Mitte (DE)
- Sun Yat-sen University Cancer Center (CN)
- NRG Oncology (US)
- University College London (GB)
- Institut Curie (FR)
- University of Hong Kong (HK)
Publication Details
- Journal
- European Journal of Cancer
- Published
- 2025-02-07
- DOI
- https://doi.org/10.1016/j.ejca.2025.115292
- Citations
- 3
- Primary Topic
- Esophageal Cancer Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 6.02
Funders
- Institut National Du Cancer
- Medical Research Council