Cost-Utility Analysis of Genomic Profiling in Directing Targeted Therapy in Advanced NSCLC in Thailand
Sequential NGS testing identified a greater number of patients with aNSCLC eligible for targeted therapies, resulting in improved survival rates and enhanced QALYs compared to single EGFR testing. However, in the context of Thailand, sequential NGS testing was not cost-effective. The single EGFR testing strategy emerged as the most cost-effective option for guiding first-line targeted therapy.
Authors
- Surakit Nathisuwan (ORCID: https://orcid.org/0000-0003-4828-4412)
- T.R. Baisamut
- Jennis Meanwatthana (ORCID: https://orcid.org/0000-0002-0308-6845)
- Saowalak Turongkaravee (ORCID: https://orcid.org/0000-0003-1897-3495)
Institutions
- Mahidol University (TH)
- Ramathibodi Hospital (TH)
Publication Details
- Journal
- Applied Health Economics and Health Policy
- Published
- 2025-02-07
- DOI
- https://doi.org/10.1007/s40258-025-00950-3
- Citations
- 1
- Primary Topic
- Lung Cancer Treatments and Mutations
- Type
- article
- Field-Weighted Citation Impact
- 1.52
Funders
- Mahidol University