Neuroprotection of retinal ganglion cells by agonism of the beta but not the alpha oestrogen receptor in the axotomized retina of male and female mice
Preclinical results may be influenced by pooling data from male and female mice. The neuroprotective effects of ERβ during the second phase of RGC loss, likely linked to neuroinflammation, suggest potential therapeutic applications for chronic conditions such as glaucoma.
Authors
- Marta Agudo‐Barriuso (ORCID: https://orcid.org/0000-0002-8566-9277)
- Caridad Galindo‐Romero (ORCID: https://orcid.org/0000-0001-9469-9868)
- Manuel Vidal‐Sanz (ORCID: https://orcid.org/0000-0002-9216-1615)
- Fernando Lucas‐Ruiz (ORCID: https://orcid.org/0000-0002-8799-6909)
- Kristy T. Rodríguez‐Ramírez
Institutions
- Instituto Murciano de Investigación Biosanitaria (ES)
- Universidad de Murcia (ES)
Publication Details
- Journal
- Acta Ophthalmologica
- Published
- 2025-02-07
- DOI
- https://doi.org/10.1111/aos.17454
- Citations
- 2
- Primary Topic
- Glaucoma and retinal disorders
- Type
- article
- Field-Weighted Citation Impact
- 3.41
Funders
- Instituto de Salud Carlos III
- Agencia Estatal de Investigación