Graves’ Disease Presenting with Section Headache: An Unusual Association

Headache is a common presenting complaint seen in the general population, with varying causes. However, headache as a primary symptom of thyroid disorders, specifically hyperthyroidism, is not routinely observed. Hyperthyroidism due to Graves’ disease presents with typical symptoms such as hyperactivity, palpitations, fatigue and weight loss and can be associated with signs such as tachycardia, tremors and ophthalmopathy. Studies have not shown any definitive association between headache and Graves’ disease. Authors hereby, describe a case of a middle-aged female patient who presented with severe bouts of headache. She was using Non Steroidal Anti-Inflammatory Drugs (NSAIDs) and other medications for pain relief, but they had no longlasting effect. An initial diagnosis of primary headache was made after ruling out other pathologies based on blood investigations, Computed Tomography (CT), and Magnetic Resonance Imaging (MRI) studies. Despite starting appropriate therapy, the patient continued to experience persistent headache and tachycardia. Further evaluation revealed hyperthyroidism, which was managed using antithyroid drugs. This, in turn, led to the resolution of her main complaint, which was headache. She required no further pain medication and was symptom-free.