Network Pharmacology and Experimental Validation to Reveal the Pharmacological Mechanisms of Gynostemma pentaphylla against Acute Pharyngitis
This study predicted the possible targets of GP in the treatment of AP through network pharmacology. The results suggest that gypenosides may inhibit the expression of inflammatory factors by regulating Pathways in cancer, P13K-AKT, and JAK-STAT signaling pathways to treat AP.
Authors
- Qiuju Huang (ORCID: https://orcid.org/0000-0001-7969-4903)
- Xiaozhong Wu (ORCID: https://orcid.org/0000-0003-1147-6250)
- Chunxi Huang (ORCID: https://orcid.org/0000-0001-8508-7165)
- Min Huang (ORCID: https://orcid.org/0000-0003-1504-4754)
- Liuyan Xu
- Jing Chen (ORCID: https://orcid.org/0000-0002-3297-9183)
- Yongqiang Li (ORCID: https://orcid.org/0000-0002-7572-2353)
- Juan Zhong (ORCID: https://orcid.org/0000-0002-1524-5946)
- Jianfeng Lü (ORCID: https://orcid.org/0000-0003-0547-0450)
- Lili Pang (ORCID: https://orcid.org/0000-0002-3945-6844)
Institutions
- Nanfang Hospital (CN)
- First People's Hospital of Nanning (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- Current Computer - Aided Drug Design
- Published
- 2025-02-04
- DOI
- https://doi.org/10.2174/0115734099324793250116133159
- Primary Topic
- Ginseng Biological Effects and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00