A Systematic Quantitative Approach to Rational Drug Design and the Discovery of Novel Human Antigen R (HuR) Inhibitors
The designed 1,4-Naphthoquinone derivatives have been found to be crucial structural motifs for the discovery of novel HuR inhibitors, which was well supported by the in-silico screening and molecular modeling methods.
Authors
- Kalyan Kumar Sethi (ORCID: https://orcid.org/0000-0002-7627-0053)
- KM Abha Mishra (ORCID: https://orcid.org/0000-0001-5628-8224)
- Paga Sudheer
- Kakade Kaushiki
- Juhi Dey
Institutions
- National Institute of Pharmaceutical Education and Research (IN)
Publication Details
- Journal
- Anti-Cancer Agents in Medicinal Chemistry
- Published
- 2025-02-07
- DOI
- https://doi.org/10.2174/0118715206354755241220062707
- Primary Topic
- Computational Drug Discovery Methods
- Type
- article
- Field-Weighted Citation Impact
- 0.00