Site-specific immunoglobulin G N-glycosylation is associated with gastric cancer progression
Alterations in subclass-specific IgG N-glycosylation represent promising biomarkers for the detection and monitoring of GC progression, potentially influenced by cytokine-driven inflammation. Understanding these changes could improve our knowledge of molecular mechanisms, aiding in diagnostic improvements and therapeutic development.
Authors
- Xi Zhu
- Weijun Shen (ORCID: https://orcid.org/0000-0003-3658-8670)
- Tingting Xu (ORCID: https://orcid.org/0000-0002-5920-808X)
- Mengting Hu (ORCID: https://orcid.org/0000-0003-1536-5400)
- Yu Chen
- Yi Que
- Shuyun Chen (ORCID: https://orcid.org/0000-0001-6116-0874)
- Si Liu (ORCID: https://orcid.org/0000-0002-5795-0782)
- Xin Liu (ORCID: https://orcid.org/0000-0003-2464-6458)
- Liming Cheng (ORCID: https://orcid.org/0000-0001-6444-5090)
- Yi Wang (ORCID: https://orcid.org/0000-0001-5979-1482)
- Yuanyuan Liu (ORCID: https://orcid.org/0000-0002-1604-2446)
- Jianmin Huang (ORCID: https://orcid.org/0000-0002-7491-3801)
- Jiajing Lin
- Honghao He
- Jianjie He
Institutions
- Fujian Medical University (CN)
- Wuhan National Laboratory for Optoelectronics (CN)
- Tongji Hospital (CN)
- Huazhong University of Science and Technology (CN)
- Fuzhou University (CN)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-02-07
- DOI
- https://doi.org/10.1186/s12885-025-13616-z
- Citations
- 3
- Primary Topic
- Glycosylation and Glycoproteins Research
- Type
- article
- Field-Weighted Citation Impact
- 2.42
Funders
- Natural Science Foundation of Fujian Province
- Huazhong University of Science and Technology
- Tongji University
- Fujian Medical University
- National Key Research and Development Program of China
- Tongji Medical College, Huazhong University of Science and Technology