Evaluation of systemic inflammatory response following transcatheter aortic valve replacement: a pathway to rational antibiotic use
Our findings indicate significant ABT overuse among TAVR recipients, likely due to misinterpretation of postoperative physiological reactions. Incorporating specific changes and thresholds of BT, WBC, and CRP post-TAVR into the RIAT score improved risk prediction for infection, underscoring its utility in enhancing antibiotic stewardship in this growing patient population.
Authors
- Ute Mons (ORCID: https://orcid.org/0000-0003-1764-6783)
- Victor Mauri (ORCID: https://orcid.org/0000-0003-2678-3501)
- Stephan Nienaber (ORCID: https://orcid.org/0000-0001-5779-7549)
- Philipp von Stein (ORCID: https://orcid.org/0000-0003-4548-3897)
- Sascha Macherey‐Meyer (ORCID: https://orcid.org/0000-0002-7080-6611)
- Stephan Baldus (ORCID: https://orcid.org/0000-0001-8259-1737)
- Jérémy Wrobel (ORCID: https://orcid.org/0000-0001-5165-2138)
- Hendrik Wienemann (ORCID: https://orcid.org/0000-0001-5810-2868)
- Henning Guthoff (ORCID: https://orcid.org/0000-0002-0979-1190)
- Valerie Lohner (ORCID: https://orcid.org/0000-0001-5589-9701)
- Matti Adam (ORCID: https://orcid.org/0000-0002-6990-8135)
- Norma Jung (ORCID: https://orcid.org/0000-0002-5740-0772)
- Maria Isabel Körber (ORCID: https://orcid.org/0000-0001-9073-9279)
- Julia Götz (ORCID: https://orcid.org/0009-0003-5003-7821)
Institutions
- University of Cologne (DE)
- University Hospital Cologne (DE)
Publication Details
- Journal
- Infection
- Published
- 2025-02-07
- DOI
- https://doi.org/10.1007/s15010-025-02485-0
- Citations
- 1
- Primary Topic
- Cardiac Valve Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.39
Funders
- Universitätsklinikum Köln