Specific molecular imaging of BALB/c model mice with Graves’ ophthalmopathy based on high expression of insulin-like growth factor 1 receptor
This study successfully established GD and GO models, reducing the duration of the immune cycle. Moreover, a peptide probe targeting IGF-1R was synthesized, enabling specific imaging of retrobulbar tissues in GO models.
Authors
- Wei Zheng (ORCID: https://orcid.org/0000-0003-1206-9243)
- Yaqian Zhou
- Yunhong Zhang (ORCID: https://orcid.org/0000-0002-2899-5068)
- Qiang Jia (ORCID: https://orcid.org/0000-0001-6198-1955)
- Ruixin Wu (ORCID: https://orcid.org/0009-0008-8222-3721)
- Ziyu Ma (ORCID: https://orcid.org/0000-0002-9801-0383)
- Wei Li (ORCID: https://orcid.org/0000-0002-0248-5510)
- Ning Li (ORCID: https://orcid.org/0000-0002-6312-5260)
- Zhiting Zhang (ORCID: https://orcid.org/0000-0001-9482-5713)
- Xuan Wang (ORCID: https://orcid.org/0000-0002-8532-5773)
- Yiming Shen
Institutions
- Shanghai Jiao Tong University (CN)
- Renji Hospital (CN)
- Tianjin Medical University General Hospital (CN)
- Shanghai Tenth People's Hospital (CN)
- Tianjin Chest Hospital (CN)
Publication Details
- Journal
- Annals of Nuclear Medicine
- Published
- 2025-02-07
- DOI
- https://doi.org/10.1007/s12149-024-02013-4
- Primary Topic
- Ophthalmology and Eye Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Tianjin Municipal Education Commission