Bacillus megaterium DSM 32963 Enhances Specialized Pro-Resolving Mediator Production from an n-3 PUFA Salt in a Dynamic Model of the Human Intestine
These findings reinforce that <i>Bacillus megaterium</i> DSM 32963 facilitates SPM production in situ from bioavailable <i>n</i>-3 PUFA in the large intestine, highlighting its use to complement eukaryotic SPM biosynthesis by the host and its possible therapeutic use for, e.g., IBD and IBS.
Authors
- Bodo Speckmann
- Paul M. Jordan (ORCID: https://orcid.org/0000-0002-8364-4236)
- Marie-Luise Vogel
- Oliver Werz (ORCID: https://orcid.org/0000-0002-5064-4379)
- Koen Venema (ORCID: https://orcid.org/0000-0001-7046-5127)
- R. Hofstetter (ORCID: https://orcid.org/0000-0002-1077-9703)
- Ellen Ehring
Institutions
- Evonik (Germany) (DE)
- Maastricht University (NL)
- Friedrich Schiller University Jena (DE)
Publication Details
- Journal
- Metabolites
- Published
- 2025-02-07
- DOI
- https://doi.org/10.3390/metabo15020105
- Citations
- 1
- Primary Topic
- Diet and metabolism studies
- Type
- article
- Field-Weighted Citation Impact
- 1.16