Rare case of endocarditis-induced iron deficiency anemia

This clinical case highlights the significance of the problem of iron deficiency anemia (IDA) in patients with bacterial endocarditis (BE) and the necessity for a detailed study of the relationships between these diseases. Objective: To investigate the correlation between BE and IDA, as well as to clarify the causal relationships between these conditions. Materials and Methods. The study is based on the examination of a clinical case of a patient with BE and IDA, treated at the Research Institute of Clinical Cardiology No. 1 in Krasnodar, including an analysis of the effectiveness of iron infusion therapies and other treatment methods. Results. A connection was found between bacteremia caused by Rothia mucilaginosa and the development of IDA. The relationship between trophic immunity and iron deficiency is also discussed. Conclusions. The study confirms the hypothesis regarding the important role of Rothia mucilaginosa in the development of endocarditis on an aortic prosthesis and in the onset of IDA. Suggestions are made regarding the mechanisms of iron consumption by this microorganism and its influence on the development of iron deficiency states, which requires further research in this area.

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Publication Details

Journal
Clinical Medicine (Russian Journal)
Published
2025-02-06
DOI
https://doi.org/10.30629/0023-2149-2024-102-9-10-767-771
Primary Topic
Infective Endocarditis Diagnosis and Management
Type
article
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article

Rare case of endocarditis-induced iron deficiency anemia

A. V. Tsekhomsky
1 links
Clinical Medicine (Russian Journal)
Infective Endocarditis Diagnosis and Management
article

Rare case of endocarditis-induced iron deficiency anemia

A. V. Tsekhomsky
article en

Abstract

This clinical case highlights the significance of the problem of iron deficiency anemia (IDA) in patients with bacterial endocarditis (BE) and the necessity for a detailed study of the relationships between these diseases. Objective: To investigate the correlation between BE and IDA, as well as to clarify the causal relationships between these conditions. Materials and Methods. The study is based on the examination of a clinical case of a patient with BE and IDA, treated at the Research Institute of Clinical Cardiology No. 1 in Krasnodar, including an analysis of the effectiveness of iron infusion therapies and other treatment methods. Results. A connection was found between bacteremia caused by Rothia mucilaginosa and the development of IDA. The relationship between trophic immunity and iron deficiency is also discussed. Conclusions. The study confirms the hypothesis regarding the important role of Rothia mucilaginosa in the development of endocarditis on an aortic prosthesis and in the onset of IDA. Suggestions are made regarding the mechanisms of iron consumption by this microorganism and its influence on the development of iron deficiency states, which requires further research in this area.

Clinical Medicine (Russian Journal)Vol. 102(9-10)
Kuban State Medical University (RU), Ministry of Health of the Russian Federation (RU)
Good health and well-being
Openalex Percentile: Top 96%
Infective Endocarditis Diagnosis and Management
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