Comparison of characteristics and immune responses between paired human nasal and bronchial epithelial organoids
NO and BO serve as robust in vitro models, faithfully recapitulating the biological characteristics of upper respiratory epithelial cells. The different regions of respiratory epithelial cells exhibit distinct immune responses, underscoring their complementary roles in exploring airway immune mechanisms and disease pathophysiology.
Authors
- Danli Lu (ORCID: https://orcid.org/0000-0003-3667-1415)
- Wenhao Yang
- Zelian Chen
- Hanmin Liu (ORCID: https://orcid.org/0000-0002-4633-911X)
- Yanan Hu (ORCID: https://orcid.org/0000-0001-6704-6108)
- Hugh Zhu (ORCID: https://orcid.org/0000-0002-5944-0989)
- Jiaxin Luo (ORCID: https://orcid.org/0009-0003-9820-1344)
- Rui Zhang (ORCID: https://orcid.org/0000-0003-4628-5729)
- Lina Chen (ORCID: https://orcid.org/0000-0001-9066-2099)
- Qiu Li (ORCID: https://orcid.org/0009-0002-9513-9138)
- Yan Li (ORCID: https://orcid.org/0000-0002-4171-4590)
Institutions
- Sichuan University (CN)
- Fudan University (CN)
- West China Second University Hospital of Sichuan University (CN)
Publication Details
- Journal
- Cell & Bioscience
- Published
- 2025-02-07
- DOI
- https://doi.org/10.1186/s13578-024-01342-1
- Citations
- 6
- Primary Topic
- Neonatal Respiratory Health Research
- Type
- article
- Field-Weighted Citation Impact
- 9.11
Funders
- National Natural Science Foundation of China
- Sichuan University
- Major Scientific and Technological Special Project of Guizhou Province
- Natural Science Foundation of Sichuan Province
- Fundamental Research Funds for the Central Universities