Unveiling GPT-4V's hidden challenges behind high accuracy on USMLE questions: Observational Study

GPT-4V achieved high accuracy on multiple-choice questions with images, highlighting its potential in medical assessments. However, significant shortcomings were observed in the quality of explanations when questions were answered incorrectly, particularly in the interpretation of images, which could not be efficiently resolved through expert interaction. These findings reveal hidden flaws in the image interpretation capabilities of GPT-4V, underscoring the need for more comprehensive evaluations beyond multiple-choice questions before integrating GPT-4V into clinical settings.

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Publication Details

Journal
Journal of Medical Internet Research
Published
2025-02-07
DOI
https://doi.org/10.2196/65146
Citations
25
Primary Topic
Artificial Intelligence in Healthcare and Education
Type
article
Field-Weighted Citation Impact
16.36
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article

Unveiling GPT-4V's hidden challenges behind high accuracy on USMLE questions: Observational Study

Zhichao Yang, Zonghai Yao, Baiyang Wang, Hong Qing Yu et al.
25 citations
Journal of Medical Internet Research
Artificial Intelligence in Healthcare and Education
16.36
article

Unveiling GPT-4V's hidden challenges behind high accuracy on USMLE questions: Observational Study

Zhichao Yang, Zonghai Yao, Baiyang Wang, Hong Qing Yu, Mahbuba Tasmin, David D. McManus, Won Seok Jang, Dan R. Berlowitz, Parth Vashisht, Feiyun Ouyang
article en
25 citations

Abstract

GPT-4V achieved high accuracy on multiple-choice questions with images, highlighting its potential in medical assessments. However, significant shortcomings were observed in the quality of explanations when questions were answered incorrectly, particularly in the interpretation of images, which could not be efficiently resolved through expert interaction. These findings reveal hidden flaws in the image interpretation capabilities of GPT-4V, underscoring the need for more comprehensive evaluations beyond multiple-choice questions before integrating GPT-4V into clinical settings.

Journal of Medical Internet ResearchVol. 27
University of Massachusetts Lowell (US), Shanghai Medical College of Fudan University (CN), University of Massachusetts Chan Medical School (US), Amherst College (US), University of Massachusetts Amherst (US), VA New England Healthcare System (US)
Quality Education
Openalex Percentile: Top 1%
Artificial Intelligence in Healthcare and Education
16.36
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Unveiling GPT-4V's hidden challenges behind high accuracy on USMLE questions: Observational Study — Zhichao Yang, Zonghai Yao, et al. · Journal of Medical Internet Research (2025) | TGRS Research Map | TGRS