Betaine enhances SCAPs chondrogenic differentiation and promotes cartilage repair in TMJOA through WDR81
Betaine promotes SCAPs chondrogenic differentiation and provided an effective candidate for TMJOA treatment. WDR81 may serve as the potential drug target through mitophagy.
Authors
- Zhaoming Wu (ORCID: https://orcid.org/0000-0002-0131-2423)
- Meiyue Wang (ORCID: https://orcid.org/0000-0003-4999-4432)
- Runtao Gao (ORCID: https://orcid.org/0000-0001-9855-8819)
- Haoqing Yang (ORCID: https://orcid.org/0000-0003-1662-9420)
- Jiaxin Song (ORCID: https://orcid.org/0000-0002-6314-2925)
- Hua Liu (ORCID: https://orcid.org/0000-0003-1651-5781)
- Yizhou Jin
- Yishu Huang (ORCID: https://orcid.org/0000-0002-4314-4288)
- Riyue Yu (ORCID: https://orcid.org/0000-0001-5778-7236)
- Xiaoyu Zheng (ORCID: https://orcid.org/0009-0006-5518-2798)
- Wanzhen Lei
Institutions
- Capital Medical University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Beijing Friendship Hospital (CN)
- Beijing Shijitan Hospital (CN)
Publication Details
- Journal
- Stem Cell Research & Therapy
- Published
- 2025-02-07
- DOI
- https://doi.org/10.1186/s13287-025-04161-4
- Citations
- 8
- Primary Topic
- Osteoarthritis Treatment and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 13.34
Funders
- National Natural Science Foundation of China