Shuang Bailian mixture enhanced the anti-cancer effect of cisplatin by regulating PI3K-Akt-Bcl 2 signaling pathway
Our study revealed the underlying mechanisms that SBLM enhanced the anti-cancer effect of CP through inhibiting the PI3K/Akt/Bcl-2 signaling pathway to induce the cells apoptosis. These results suggest that SBLM could serve as a promising adjuvant in chemotherapeutic regimens for EC.
Authors
- Guoxin Huang (ORCID: https://orcid.org/0000-0001-8128-7135)
- Qingnan Li
- Yilin Zheng
- Xiongyu Meng
- Guohai Huang
- Weijin Zhang (ORCID: https://orcid.org/0009-0009-3020-3232)
- Xiaoyan Li (ORCID: https://orcid.org/0000-0001-5031-8875)
- Yuanfeng Zhang (ORCID: https://orcid.org/0000-0002-4330-072X)
- Xiaohua Yao
Institutions
- Zhejiang Chinese Medical University (CN)
- Research Institute of Tropical Forestry (CN)
- Shantou Central Hospital (CN)
Publication Details
- Journal
- Journal of Ethnopharmacology
- Published
- 2025-02-07
- DOI
- https://doi.org/10.1016/j.jep.2025.119462
- Citations
- 2
- Primary Topic
- Cancer Mechanisms and Therapy
- Type
- article
- Field-Weighted Citation Impact
- 2.94