Benign mature teratoma of the conus medullaris in a 57-year-old-female: case report and literature review

Abstract Background The diagnosis of a mature teratoma in the conus medullaris is extremely rare, and few cases are reported in the literature. Case presentation We present a case of a 57-year-old woman who was referred from the neurology department for sudden weakness of the lower limbs. The patient has a medical history of chronic low back pain. She has normal bowel and bladder function. The neurological examination found reduced lower limb power, where the right and left proximal power were 0/5 and 2/5, respectively. Spinal cord MRI was performed, showing a well-delineated intramedullary mass at the level of the conus medullaris. Emergent surgery was performed using a surgical microscope, and the patient underwent a total resection of the tumor after T12–L2 bilateral laminectomy. The histological results were consistent with a benign mature teratoma and no additional postoperative neurological deficits were reported by the patient. Conclusion Adult’s cases of mature teratoma of the conus medullaris are extremely rare. The tumor present various symptoms primarily caused by compression, and definitive diagnosis is made by histological examination. Surgical excision is the most effective treatment, and total resection should be the aim. However, the surgical excision should be made under neurophysiological monitoring to avoid some injury to the surrounding neural tissue. Furthermore, the paucity of literature on the Adjuvant therapy for spinal teratoma is a challenge for neurosurgery for aiming of total resection.

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Journal
The Egyptian Journal of Neurosurgery : the official publication of the Egyptian Society of Neurological Surgeons/Egyptian journal of neurosurgery
Published
2025-02-07
DOI
https://doi.org/10.1186/s41984-025-00366-0
Primary Topic
Spinal Dysraphism and Malformations
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article
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article

Benign mature teratoma of the conus medullaris in a 57-year-old-female: case report and literature review

Dramane Cissé, Mohammed El Faïz Chaoui, F. Lakhdar, Oualid Mohammed Hmamouche et al.
The Egyptian Journal of Neurosurgery : the official publication of the Egyptian Society of Neurological Surgeons/Egyptian journal of neurosurgery
Spinal Dysraphism and Malformations
article

Benign mature teratoma of the conus medullaris in a 57-year-old-female: case report and literature review

Dramane Cissé, Mohammed El Faïz Chaoui, F. Lakhdar, Oualid Mohammed Hmamouche, Khalid Chakour, Mohammed Benzagmout, Daniel Yamba Yamba
article en

Abstract

Abstract Background The diagnosis of a mature teratoma in the conus medullaris is extremely rare, and few cases are reported in the literature. Case presentation We present a case of a 57-year-old woman who was referred from the neurology department for sudden weakness of the lower limbs. The patient has a medical history of chronic low back pain. She has normal bowel and bladder function. The neurological examination found reduced lower limb power, where the right and left proximal power were 0/5 and 2/5, respectively. Spinal cord MRI was performed, showing a well-delineated intramedullary mass at the level of the conus medullaris. Emergent surgery was performed using a surgical microscope, and the patient underwent a total resection of the tumor after T12–L2 bilateral laminectomy. The histological results were consistent with a benign mature teratoma and no additional postoperative neurological deficits were reported by the patient. Conclusion Adult’s cases of mature teratoma of the conus medullaris are extremely rare. The tumor present various symptoms primarily caused by compression, and definitive diagnosis is made by histological examination. Surgical excision is the most effective treatment, and total resection should be the aim. However, the surgical excision should be made under neurophysiological monitoring to avoid some injury to the surrounding neural tissue. Furthermore, the paucity of literature on the Adjuvant therapy for spinal teratoma is a challenge for neurosurgery for aiming of total resection.

The Egyptian Journal of Neurosurgery : the official publication of the Egyptian Society of Neurological Surgeons/Egyptian journal of neurosurgeryVol. 40(1)
Centre Hospitalier Universitaire Hassan II (MA)
Good health and well-being
Openalex Percentile: Top 97%
Spinal Dysraphism and Malformations
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Benign mature teratoma of the conus medullaris in a 57-year-old-female: case report and literature review — Dramane Cissé, Mohammed El Faïz Chaoui, et al. · The Egyptian Journal of Neurosurgery : the official publication of the Egyptian Society of Neurological Surgeons/Egyptian journal of neurosurgery (2025) | TGRS Research Map | TGRS