Human Tendon‐on‐a‐Chip for Modeling the Myofibroblast Microenvironment in Peritendinous Fibrosis (Adv. Healthcare Mater. 4/2025)
Tendon-on-a-ChipA novel human Tendon-on-a-Chip model replicates aspects of the myofibroblast microenvironment in peritendinous adhesions.This chip sheds light on cellular and molecular crosstalk between immune cells, endothelial cells, and myofibroblasts, offering a powerful tool for drug testing and de-risking drug development for fibrotic diseases.
Authors
- Isabelle Linares
- Raquel E. Ajalik
- Rahul G. Alenchery (ORCID: https://orcid.org/0000-0002-8547-8622)
- Benjamin L. Miller (ORCID: https://orcid.org/0000-0001-9168-8047)
- Victor Z. Zhang
- Hani A. Awad (ORCID: https://orcid.org/0000-0003-2197-2610)
- Terry W. Wright (ORCID: https://orcid.org/0000-0001-6531-2214)
- James L. McGrath
Publication Details
- Journal
- Advanced Healthcare Materials
- Published
- 2025-02-01
- DOI
- https://doi.org/10.1002/adhm.202570024
- Primary Topic
- Medical and Biological Ozone Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00