Bioinformatics insights into mitochondrial and immune gene regulation in Alzheimer's disease
Five mitochondrial and immune biomarkers, i.e., TSPO, HIGD1A, NDUFAB1, NT5DC3, and MRPS30, with diagnostic value in Alzheimer's disease, were screened by machine-learning algorithmic models, which will be a guide for future clinical research of Alzheimer's disease in the mitochondria-immunity-related direction.
Authors
- Yongsheng He (ORCID: https://orcid.org/0000-0001-6352-6286)
- Meng Tian (ORCID: https://orcid.org/0000-0001-7273-7683)
- Hui Li (ORCID: https://orcid.org/0000-0002-0406-9203)
- Yazhuo Zhang (ORCID: https://orcid.org/0000-0002-8583-2580)
- Ye Yuan (ORCID: https://orcid.org/0000-0003-0154-5312)
Institutions
- Second People's Hospital of Yunnan Province (CN)
- Yuntianhua Group (China) (CN)
Publication Details
- Journal
- European journal of medical research
- Published
- 2025-02-08
- DOI
- https://doi.org/10.1186/s40001-025-02297-w
- Citations
- 3
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 3.49