The prognostic and predictive value of the luminal-like subtype in hormone receptor-positive breast cancer: an analysis of the DATA trial
In patients with hormone receptor-positive breast cancer, the luminal B-like subtype was associated with a significantly worse prognosis when compared with the luminal A-like subtype. Extended anastrozole therapy halved the risk of DR and BCSM in patients with luminal A-like tumours, whereas no effect was seen in patients with luminal B-like tumours.
Authors
- Maurice J.C. van der Sangen (ORCID: https://orcid.org/0000-0003-1866-7367)
- Karlijn Susanna Francisca Maria Hermans (ORCID: https://orcid.org/0000-0002-7629-0820)
- Sandra M. E. Geurts (ORCID: https://orcid.org/0000-0002-4265-9968)
- Judith R. Kroep (ORCID: https://orcid.org/0000-0003-2671-1903)
- S W M Lammers (ORCID: https://orcid.org/0000-0002-8279-585X)
- Loes F. S. Kooreman (ORCID: https://orcid.org/0000-0001-8226-8665)
- Carolien H. Smorenburg (ORCID: https://orcid.org/0000-0002-1046-2634)
- Vivianne C. G. Tjan‐Heijnen (ORCID: https://orcid.org/0000-0002-3935-7440)
- Alexander L.T. Imholz
- S. Linn (ORCID: https://orcid.org/0000-0001-5471-5034)
- W Roos
- Franchette W.P.J. van den Berkmortel
- A.H. Honkoop
- Ingeborg J. H. Vriens
- Astrid C P Swinkels (ORCID: https://orcid.org/0000-0002-0047-0948)
Institutions
- Radboud University Nijmegen (NL)
- Leiden University Medical Center (NL)
- Maastricht University Medical Centre (NL)
- Catharina Ziekenhuis (NL)
- The Netherlands Cancer Institute (NL)
- University Medical Center Utrecht (NL)
- Oncode Institute (NL)
- Ziekenhuis Gelderse Vallei (NL)
- Cancer Genomics Centre (NL)
- Zuyderland Medisch Centrum (NL)
- Netherlands Comprehensive Cancer Organisation (NL)
- Isala (NL)
- Deventer Ziekenhuis (NL)
Publication Details
- Journal
- ESMO Open
- Published
- 2025-02-01
- DOI
- https://doi.org/10.1016/j.esmoop.2025.104154
- Citations
- 13
- Primary Topic
- Breast Cancer Treatment Studies
- Type
- article
- Field-Weighted Citation Impact
- 12.17
Funders
- AstraZeneca