Cumulative Excess Body Mass Index and MGUS Progression to Myeloma
This cohort study found that, for patients with BMI 18.5 to less than 25 at the time of MGUS diagnosis, cumulative exposure to BMI 25 or greater was associated with an increased risk of progression. These findings suggest that for these patients, maintaining a healthy and stable weight following MGUS diagnosis may prevent progression to MM.
Authors
- Su‐Hsin Chang (ORCID: https://orcid.org/0000-0001-5872-9556)
- Ekaterina Proskuriakova (ORCID: https://orcid.org/0000-0003-2730-2271)
- Lawrence Liu (ORCID: https://orcid.org/0000-0001-8559-7739)
- Graham A. Colditz (ORCID: https://orcid.org/0000-0002-7307-0291)
- Kristen M. Sanfilippo (ORCID: https://orcid.org/0000-0002-0433-7845)
- Murali Janakiram (ORCID: https://orcid.org/0000-0001-9323-8007)
- Mengmeng Ji (ORCID: https://orcid.org/0000-0002-1205-0369)
- Martin William Schoen (ORCID: https://orcid.org/0000-0001-6388-5553)
- Kenneth R. Carson (ORCID: https://orcid.org/0000-0001-7471-9542)
- Celine M. Vachon
- Alissa Visram (ORCID: https://orcid.org/0000-0002-7201-4642)
- Nikhil Grandhi
- Mei Wang (ORCID: https://orcid.org/0000-0002-3560-9460)
- Theodore Thomas
Institutions
- Northwestern University (US)
- Mayo Clinic (US)
- University of Ottawa (CA)
- Washington University in St. Louis (US)
- Ottawa Hospital (CA)
- Mount Sinai Hospital (US)
- St. Louis VA Medical Center (US)
- City of Hope (US)
- Ottawa Hospital Research Institute (CA)
- Saint Louis University (US)
Publication Details
- Journal
- JAMA Network Open
- Published
- 2025-02-07
- DOI
- https://doi.org/10.1001/jamanetworkopen.2024.58585
- Citations
- 4
- Primary Topic
- Multiple Myeloma Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 7.08