CD36 inhibition enhances the anti-proliferative effects of PI3K inhibitors in PTEN-loss anti-HER2 resistant breast cancer cells
Simultaneously targeting the PI3K signaling pathway and exogenous FA uptake could potentially be advantageous for patients with PTEN-loss anti-HER2 resistant breast cancer.
Authors
- You‐Yu Liu
- Ting‐Yu Kao
- Sin-Tian Wang (ORCID: https://orcid.org/0000-0002-1341-9930)
- Wei‐Pang Chung (ORCID: https://orcid.org/0000-0001-8485-270X)
- Wei-Lun Huang (ORCID: https://orcid.org/0009-0000-0523-8585)
- Hui-Ping Hsu
- Kung-Chia Young
Institutions
- National Cheng Kung University Hospital (TW)
- National Cheng Kung University (TW)
Publication Details
- Journal
- Cancer & Metabolism
- Published
- 2025-02-07
- DOI
- https://doi.org/10.1186/s40170-025-00375-5
- Citations
- 7
- Primary Topic
- PI3K/AKT/mTOR signaling in cancer
- Type
- article
- Field-Weighted Citation Impact
- 5.64
Funders
- Ministry of Education, India
- National Cheng Kung University Hospital
- National Cheng Kung University
- National Science and Technology Council