The role of mNGS in the diagnosis of talaromycosis and case series
Traditional diagnostic methods are limited by factors such as the long time and low sensitivity of fungal culture, the effect of prior antibiotic treatment, the invasiveness and complexities of tissue biopsies, and so on. Emerging technologies, particularly mNGS, offer advantages such as rapid processing, high accuracy, and comprehensive pathogen coverage, significantly reducing the risk of missed diagnoses and facilitating timely intervention.
Authors
- Juan Du (ORCID: https://orcid.org/0000-0003-1467-1203)
- Minya Lu
- Wang Yao (ORCID: https://orcid.org/0000-0003-2883-4528)
- Xin-Fei Chen
- Shenli Jia (ORCID: https://orcid.org/0000-0003-2782-2234)
- Dongmei Wen (ORCID: https://orcid.org/0000-0003-4384-9584)
- X R Li
- Dong Zhang (ORCID: https://orcid.org/0000-0001-8186-4692)
- Qiwen Yang
- Jing Zhao (ORCID: https://orcid.org/0000-0002-2273-238X)
- Yi Gao
- Jiayu Guo (ORCID: https://orcid.org/0000-0002-3616-757X)
- Huiting Su
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking Union Medical College Hospital (CN)
- National Clinical Research Center for Digestive Diseases (CN)
- Ministry of Education (RO)
- Beijing Aerospace General Hospital (CN)
- Shanghai East Hospital (CN)
Publication Details
- Journal
- BMC Infectious Diseases
- Published
- 2025-02-07
- DOI
- https://doi.org/10.1186/s12879-025-10529-x
- Citations
- 6
- Primary Topic
- Fungal Infections and Studies
- Type
- article
- Field-Weighted Citation Impact
- 8.13
Funders
- National Natural Science Foundation of China
- Chinese Academy of Medical Sciences
- Peking Union Medical College Hospital
- National Key Research and Development Program of China